Conformational heterogeneity and bubble dynamics in single bacterial transcription initiation complexes

Transcription initiation is a major step in gene regulation for all organisms. In bacteria, the promoter DNA is first recognized by RNA polymerase (RNAP) to yield an initial closed complex. This complex subsequently undergoes conformational changes resulting in DNA strand separation to form a transc...

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Detalles Bibliográficos
Autores principales: Duchi, Diego, Gryte, Kristofer, Robb, Nicole C, Morichaud, Zakia, Sheppard, Carol, Brodolin, Konstantin, Wigneshweraraj, Sivaramesh, Kapanidis, Achillefs N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778504/
https://www.ncbi.nlm.nih.gov/pubmed/29177430
http://dx.doi.org/10.1093/nar/gkx1146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778504/
https://www.ncbi.nlm.nih.gov/pubmed/29177430
http://dx.doi.org/10.1093/nar/gkx1146

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