Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair

The DNA damage response (DDR) is an extensive signaling network that is robustly mobilized by DNA double-strand breaks (DSBs). The primary transducer of the DSB response is the protein kinase, ataxia-telangiectasia, mutated (ATM). Here, we establish nuclear poly(A)-binding protein 1 (PABPN1) as a no...

Descripción completa

Detalles Bibliográficos
Autores principales: Gavish-Izakson, Michal, Velpula, Bhagya Bhavana, Elkon, Ran, Prados-Carvajal, Rosario, Barnabas, Georgina D, Ugalde, Alejandro Pineiro, Agami, Reuven, Geiger, Tamar, Huertas, Pablo, Ziv, Yael, Shiloh, Yosef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778506/
https://www.ncbi.nlm.nih.gov/pubmed/29253183
http://dx.doi.org/10.1093/nar/gkx1240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778506/
https://www.ncbi.nlm.nih.gov/pubmed/29253183
http://dx.doi.org/10.1093/nar/gkx1240

Ejemplares similares