E-motif formed by extrahelical cytosine bases in DNA homoduplexes of trinucleotide and hexanucleotide repeats

Atypical DNA secondary structures play an important role in expandable trinucleotide repeat (TR) and hexanucleotide repeat (HR) diseases. The cytosine mismatches in C-rich homoduplexes and hairpin stems are weakly bonded; experiments show that for certain sequences these may flip out of the helix co...

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Detalles Bibliográficos
Autores principales: Pan, Feng, Zhang, Yuan, Man, Viet Hoang, Roland, Christopher, Sagui, Celeste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778509/
https://www.ncbi.nlm.nih.gov/pubmed/29190385
http://dx.doi.org/10.1093/nar/gkx1186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778509/
https://www.ncbi.nlm.nih.gov/pubmed/29190385
http://dx.doi.org/10.1093/nar/gkx1186

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