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Rolling circle amplification shows a sinusoidal template length-dependent amplification bias

Biophysical properties of DNA such as its longitudinal and torsional persistence length govern many processes and phenomena in biology, DNA nanotechnology and biotechnology. It has, for example, long been known that the circularization efficiency of short DNA fragments shows a periodic pattern where...

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Detalles Bibliográficos
Autores principales: Joffroy, Bastian, Uca, Yavuz O, Prešern, Domen, Doye, Jonathan P. K, Schmidt, Thorsten L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778537/
https://www.ncbi.nlm.nih.gov/pubmed/29237070
http://dx.doi.org/10.1093/nar/gkx1238