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Protective effect of FGF-2 and low-molecular-weight heparin/protamine nanoparticles on radiation-induced healing-impaired wound repair in rats

We examined the effectiveness of localized administration of fibroblast growth factor-2 containing low-molecular-weight heparin/protamine nanoparticles (FGF-2&LMWH/P NPs) on apoptosis in vivo and on healing of radiation-induced skin injury in a rat model. FGF-2 binds onto LMWH/P NPs, which can s...

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Detalles Bibliográficos
Autores principales: Kinoda, Jun, Ishihara, Masayuki, Nakamura, Shingo, Fujita, Masanori, Fukuda, Koichi, Sato, Yoko, Yokoe, Hidetaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778538/
https://www.ncbi.nlm.nih.gov/pubmed/29121251
http://dx.doi.org/10.1093/jrr/rrx044