Dynamics of the excised base release in thymine DNA glycosylase during DNA repair process

Thymine DNA glycosylase (TDG) initiates base excision repair by cleaving the N-glycosidic bond between the sugar and target base. After catalysis, the release of excised base is a requisite step to terminate the catalytic cycle and liberate the TDG for the following enzymatic reactions. However, an...

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Detalles Bibliográficos
Autores principales: Da, Lin-Tai, Shi, Yi, Ning, Guodong, Yu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778594/
https://www.ncbi.nlm.nih.gov/pubmed/29253232
http://dx.doi.org/10.1093/nar/gkx1261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778594/
https://www.ncbi.nlm.nih.gov/pubmed/29253232
http://dx.doi.org/10.1093/nar/gkx1261

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