Editing activity for eliminating mischarged tRNAs is essential in mammalian mitochondria

Accuracy of protein synthesis is enabled by the selection of amino acids for tRNA charging by aminoacyl-tRNA synthetases (ARSs), and further enhanced by the proofreading functions of some of these enzymes for eliminating tRNAs mischarged with noncognate amino acids. Mouse models of editing-defective...

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Detalles Bibliográficos
Autores principales: Hilander, Taru, Zhou, Xiao-Long, Konovalova, Svetlana, Zhang, Fu-Ping, Euro, Liliya, Chilov, Dmitri, Poutanen, Matti, Chihade, Joseph, Wang, En-Duo, Tyynismaa, Henna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778596/
https://www.ncbi.nlm.nih.gov/pubmed/29228266
http://dx.doi.org/10.1093/nar/gkx1231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778596/
https://www.ncbi.nlm.nih.gov/pubmed/29228266
http://dx.doi.org/10.1093/nar/gkx1231

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