Reconstitution of the CstF complex unveils a regulatory role for CstF-50 in recognition of 3′-end processing signals

Cleavage stimulation factor (CstF) is a highly conserved protein complex composed of three subunits that recognizes G/U-rich sequences downstream of the polyadenylation signal of eukaryotic mRNAs. While CstF has been identified over 25 years ago, the architecture and contribution of each subunit to...

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Detalles Bibliográficos
Autores principales: Yang, Wen, Hsu, Peter L, Yang, Fan, Song, Jae-Eun, Varani, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
NAR Breakthrough Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778602/
https://www.ncbi.nlm.nih.gov/pubmed/29186539
http://dx.doi.org/10.1093/nar/gkx1177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778602/
https://www.ncbi.nlm.nih.gov/pubmed/29186539
http://dx.doi.org/10.1093/nar/gkx1177

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