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Reconstitution of the CstF complex unveils a regulatory role for CstF-50 in recognition of 3′-end processing signals
Cleavage stimulation factor (CstF) is a highly conserved protein complex composed of three subunits that recognizes G/U-rich sequences downstream of the polyadenylation signal of eukaryotic mRNAs. While CstF has been identified over 25 years ago, the architecture and contribution of each subunit to...
Autores principales: | Yang, Wen, Hsu, Peter L, Yang, Fan, Song, Jae-Eun, Varani, Gabriele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778602/ https://www.ncbi.nlm.nih.gov/pubmed/29186539 http://dx.doi.org/10.1093/nar/gkx1177 |
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