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Alternative start and termination sites of transcription drive most transcript isoform differences across human tissues

Most human genes generate multiple transcript isoforms. The differential expression of these isoforms can help specify cell types. Diverse transcript isoforms arise from the use of alternative transcription start sites, polyadenylation sites and splice sites; however, the relative contribution of th...

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Detalles Bibliográficos
Autores principales: Reyes, Alejandro, Huber, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778607/
https://www.ncbi.nlm.nih.gov/pubmed/29202200
http://dx.doi.org/10.1093/nar/gkx1165