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Alternative start and termination sites of transcription drive most transcript isoform differences across human tissues
Most human genes generate multiple transcript isoforms. The differential expression of these isoforms can help specify cell types. Diverse transcript isoforms arise from the use of alternative transcription start sites, polyadenylation sites and splice sites; however, the relative contribution of th...
Autores principales: | Reyes, Alejandro, Huber, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778607/ https://www.ncbi.nlm.nih.gov/pubmed/29202200 http://dx.doi.org/10.1093/nar/gkx1165 |
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