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Primaquine ineligibility in anti-relapse therapy of Plasmodium vivax malaria: the problem of G6PD deficiency and cytochrome P-450 2D6 polymorphisms

The hypnozoite reservoir of Plasmodium vivax represents both the greatest obstacle and opportunity for ultimately eradicating this species. It is silent and cannot be diagnosed until it awakens and provokes a clinical attack with attendant morbidity, risk of mortality, and opportunities for onward t...

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Detalles Bibliográficos
Autores principales: Baird, J. Kevin, Battle, Katherine E., Howes, Rosalind E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778616/
https://www.ncbi.nlm.nih.gov/pubmed/29357870
http://dx.doi.org/10.1186/s12936-018-2190-z