Chemotherapy weakly contributes to predicted neoantigen expression in ovarian cancer

BACKGROUND: Patients with highly mutated tumors, such as melanoma or smoking-related lung cancer, have higher rates of response to immune checkpoint blockade therapy, perhaps due to increased neoantigen expression. Many chemotherapies including platinum compounds are known to be mutagenic, but the i...

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Detalles Bibliográficos
Autores principales: O’Donnell, Timothy, Christie, Elizabeth L., Ahuja, Arun, Buros, Jacqueline, Aksoy, B. Arman, Bowtell, David D. L., Snyder, Alexandra, Hammerbacher, Jeff
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778667/
https://www.ncbi.nlm.nih.gov/pubmed/29357823
http://dx.doi.org/10.1186/s12885-017-3825-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778667/
https://www.ncbi.nlm.nih.gov/pubmed/29357823
http://dx.doi.org/10.1186/s12885-017-3825-0

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