A synthetic cell-penetrating peptide derived from nuclear localization signal of EPS8 exerts anticancer activity against acute myeloid leukemia

BACKGROUND: Oncogenic roles of epidermal growth factor receptor pathway substrate no.8 (EPS8) have been widely reported in various tumors, making targeting of EPS8 an appealing prospect. Here, we describe the role of EPS8 in acute myeloid leukemia (AML) and consider the potential of EPS8 as an anti-...

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Detalles Bibliográficos
Autores principales: Chen, Yiran, Xie, Xiaoling, Wu, Anqin, Wang, Lei, Hu, Yuxing, Zhang, Honghao, Li, Yuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778704/
https://www.ncbi.nlm.nih.gov/pubmed/29357910
http://dx.doi.org/10.1186/s13046-018-0682-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778704/
https://www.ncbi.nlm.nih.gov/pubmed/29357910
http://dx.doi.org/10.1186/s13046-018-0682-x

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