AGE-induced neuronal cell death is enhanced in G2019S LRRK2 mutation with increased RAGE expression

BACKGROUND: Leucine-rich repeat kinase 2 (LRRK2) mutations represent the most common genetic cause of sporadic and familial Parkinson’s disease (PD). Especially, LRRK2 G2019S missense mutation has been identified as the most prevalent genetic cause in the late-onset PD. Advanced glycation end produc...

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Detalles Bibliográficos
Autores principales: Cho, Hyun Jin, Xie, Chengsong, Cai, Huaibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778750/
https://www.ncbi.nlm.nih.gov/pubmed/29387348
http://dx.doi.org/10.1186/s40035-018-0106-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778750/
https://www.ncbi.nlm.nih.gov/pubmed/29387348
http://dx.doi.org/10.1186/s40035-018-0106-z

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