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Overnight auto-adjusting continuous airway pressure + standard care compared with standard care alone in the prevention of morbidity in sickle cell disease phase II (POMS2b): study protocol for a randomised controlled trial

BACKGROUND: In addition to pain, sickle cell anaemia (HbSS) complications include neurocognitive difficulties in attention and processing speed associated with low daytime and night-time oxygen saturation compounded by obstructive sleep apnoea (OSA). In the general population OSA is treated with con...

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Detalles Bibliográficos
Autores principales: Howard, Jo, Slee, April E., Skene, Simon, Inusa, Baba, Kawadler, Jamie, Downes, Michelle, Gavlak, Johanna, Koelbel, Melanie, Stotesbury, Hanne, Chorozoglou, Maria, Tebbs, Susan, Chakravorty, Subarna, Awogbade, Moji, Rees, David C., Gupta, Atul, Murphy, Patrick B., Hart, Nicholas, Sahota, Sati, Nwosu, Carol, Gwam, Maureen, Saunders, Dawn, Muthurangu, Vivek, Barber, Nathaniel, Ako, Emmanuel, Thein, Swee Lay, Marshall, Melanie, Reading, Isabel C, Cheng, Man Ying Edith, Kirkham, Fenella J., Liossi, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778753/
https://www.ncbi.nlm.nih.gov/pubmed/29357947
http://dx.doi.org/10.1186/s13063-017-2419-0