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Two-step interphase microtubule disassembly aids spindle morphogenesis

BACKGROUND: Entry into mitosis triggers profound changes in cell shape and cytoskeletal organisation. Here, by studying microtubule remodelling in human flat mitotic cells, we identify a two-step process of interphase microtubule disassembly. RESULTS: First, a microtubule-stabilising protein, Enscon...

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Detalles Bibliográficos
Autores principales: Mchedlishvili, Nunu, Matthews, Helen K., Corrigan, Adam, Baum, Buzz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778756/
https://www.ncbi.nlm.nih.gov/pubmed/29361957
http://dx.doi.org/10.1186/s12915-017-0478-z