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Biomarkers of cytokine release syndrome and neurotoxicity related to CAR-T cell therapy

Severe cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T cell (CAR-T) therapy can be life-threatening in some cases, and management of those toxicities is still a great challenge for physicians. Researchers hope to understand the pathophysiology of CRS and neuro...

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Detalles Bibliográficos
Autores principales: Wang, Zhenguang, Han, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778792/
https://www.ncbi.nlm.nih.gov/pubmed/29387417
http://dx.doi.org/10.1186/s40364-018-0116-0