MS AHI1 genetic risk promotes IFNγ(+) CD4(+) T cells

OBJECTIVE: To study the influence of the Abelson helper integration site 1 (AHI1) locus associated with MS susceptibility on CD4(+) T cell function. METHODS: We characterized the chromatin state of T cells in the MS-associated AHI1 linkage disequilibrium (LD) block. The expression and the role of th...

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Detalles Bibliográficos
Autores principales: Kaskow, Belinda J., Buttrick, Thomas S., Klein, Hans-Ulrich, White, Charles, Bourgeois, Justin R., Ferland, Russell J., Patsopoulos, Nikolaos, Bradshaw, Elizabeth M., De Jager, Philip L., Elyaman, Wassim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778810/
https://www.ncbi.nlm.nih.gov/pubmed/29379820
http://dx.doi.org/10.1212/NXI.0000000000000414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778810/
https://www.ncbi.nlm.nih.gov/pubmed/29379820
http://dx.doi.org/10.1212/NXI.0000000000000414

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