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MS AHI1 genetic risk promotes IFNγ(+) CD4(+) T cells
OBJECTIVE: To study the influence of the Abelson helper integration site 1 (AHI1) locus associated with MS susceptibility on CD4(+) T cell function. METHODS: We characterized the chromatin state of T cells in the MS-associated AHI1 linkage disequilibrium (LD) block. The expression and the role of th...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Lippincott Williams & Wilkins
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778810/ https://www.ncbi.nlm.nih.gov/pubmed/29379820 http://dx.doi.org/10.1212/NXI.0000000000000414 |