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Cranial irradiation inhibits hippocampal neurogenesis via DNMT1 and DNMT3A
Impairment of neurogenesis in the hippocampus following whole-brain irradiation is the most important mechanism of radiation-induced cognitive dysfunction. However, the underlying mechanism remains obscure, meaning an ideal therapeutic target has not been identified. Evidence indicates that DNA meth...
Autores principales: | Ji, Shengjun, Ding, Xin, Ji, Jiang, Wu, Haohao, Sun, Rui, Li, Xiaoyang, Zhang, Liyuan, Tian, Ye |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778827/ https://www.ncbi.nlm.nih.gov/pubmed/29435016 http://dx.doi.org/10.3892/ol.2017.7643 |
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