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High expression of carcinoembryonic antigen and telomerase reverse transcriptase in circulating tumor cells is associated with poor clinical response to the immune checkpoint inhibitor nivolumab

The present study aimed to enrich circulating tumor cells (CTCs) from blood samples using a new size-sorting CTC chip. The present study also set out to identify a blood sensitivity marker for the immune checkpoint inhibitor nivolumab in patients with advanced, pre-treatment lung cancer. The CTC sor...

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Detalles Bibliográficos
Autores principales: Bao, Halin, Bai, Tuya, Takata, Koji, Yokobori, Takehiko, Ohnaga, Takashi, Hisada, Takeshi, Maeno, Toshitaka, Bao, Pinjie, Yoshida, Tomonori, Kumakura, Yuji, Honjo, Hiroaki, Sakai, Makoto, Sohda, Makoto, Fukuchi, Minoru, Altan, Bolag, Handa, Tadashi, Ide, Munenori, Miyazaki, Tatsuya, Ogata, Kyoichi, Oyama, Tetsunari, Shimizu, Kimihiro, Mogi, Akira, Asao, Takayuki, Shirabe, Ken, Kuwano, Hiroyuki, Kaira, Kyoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778830/
https://www.ncbi.nlm.nih.gov/pubmed/29435038
http://dx.doi.org/10.3892/ol.2017.7671