Mitochondrial ROS contribute to oridonin-induced HepG2 apoptosis through PARP activation

Oridonin, the main active constituent of Rabdosia rubescens, is known to exert antitumor activity via the induction of apoptosis in numerous types of human cancer cells. However, the underlying regulatory mechanisms of mitochondrial ROS in oridonin-induced HepG2 apoptosis remain largely unknown, due...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoning, Kang, Jingjing, Wang, Hui, Huang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778846/
https://www.ncbi.nlm.nih.gov/pubmed/29435014
http://dx.doi.org/10.3892/ol.2017.7665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778846/
https://www.ncbi.nlm.nih.gov/pubmed/29435014
http://dx.doi.org/10.3892/ol.2017.7665

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