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Mitochondrial ROS contribute to oridonin-induced HepG2 apoptosis through PARP activation
Oridonin, the main active constituent of Rabdosia rubescens, is known to exert antitumor activity via the induction of apoptosis in numerous types of human cancer cells. However, the underlying regulatory mechanisms of mitochondrial ROS in oridonin-induced HepG2 apoptosis remain largely unknown, due...
Autores principales: | Liu, Xiaoning, Kang, Jingjing, Wang, Hui, Huang, Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778846/ https://www.ncbi.nlm.nih.gov/pubmed/29435014 http://dx.doi.org/10.3892/ol.2017.7665 |
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