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Chloroquine potentiates the anticancer effect of sunitinib on renal cell carcinoma by inhibiting autophagy and inducing apoptosis

Sunitinib based adjuvant chemotherapy combined with chloroquine (CQ) for the treatment of renal cell carcinoma (RCC) is in clinical trials; however, its anti-RCC effect and the mechanism remain unclear. In the present study, the anti-RCC effect of sunitinib with CQ and the underlying mechanism was i...

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Detalles Bibliográficos
Autores principales: Li, Man-Li, Xu, You-Zhi, Lu, Wen-Jie, Li, Yong-Huai, Tan, Shi-Sheng, Lin, Hong-Jun, Wu, Tian-Ming, Li, Yan, Wang, Si-Ying, Zhao, Ying-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778883/
https://www.ncbi.nlm.nih.gov/pubmed/29435010
http://dx.doi.org/10.3892/ol.2017.7635