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Chloroquine potentiates the anticancer effect of sunitinib on renal cell carcinoma by inhibiting autophagy and inducing apoptosis
Sunitinib based adjuvant chemotherapy combined with chloroquine (CQ) for the treatment of renal cell carcinoma (RCC) is in clinical trials; however, its anti-RCC effect and the mechanism remain unclear. In the present study, the anti-RCC effect of sunitinib with CQ and the underlying mechanism was i...
Autores principales: | Li, Man-Li, Xu, You-Zhi, Lu, Wen-Jie, Li, Yong-Huai, Tan, Shi-Sheng, Lin, Hong-Jun, Wu, Tian-Ming, Li, Yan, Wang, Si-Ying, Zhao, Ying-Lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778883/ https://www.ncbi.nlm.nih.gov/pubmed/29435010 http://dx.doi.org/10.3892/ol.2017.7635 |
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