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Characterization of mutations in BRCA1/2 and the relationship with clinic-pathological features of breast cancer in a hereditarily high-risk sample of chinese population

The database of BRCA1/2 mutations in Chinese population remains incomplete at present. Therefore, the present study aimed to report specific harmful BRCA1/2 mutations in the Chinese population and discuss the clinicopathological features in mutation carriers. BRCA1/2 germline mutation tests for 71 p...

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Detalles Bibliográficos
Autores principales: Fang, Min, Zhu, Li, Li, Hengyu, Li, Xizhou, Wu, Yanmei, Wu, Kainan, Lin, Jian, Sheng, Yuan, Yu, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778890/
https://www.ncbi.nlm.nih.gov/pubmed/29435039
http://dx.doi.org/10.3892/ol.2017.7717