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Long‐Term Exposure of Fine Particulate Matter Causes Hypertension by Impaired Renal D(1) Receptor–Mediated Sodium Excretion via Upregulation of G‐Protein–Coupled Receptor Kinase Type 4 Expression in Sprague‐Dawley Rats
BACKGROUND: Epidemiological evidence supports an important association between air pollution exposure and hypertension. However, the mechanisms are not clear. METHODS AND RESULTS: Our present study found that long‐term exposure to fine particulate matter (PM(2.5)) causes hypertension and impairs ren...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778966/ https://www.ncbi.nlm.nih.gov/pubmed/29307864 http://dx.doi.org/10.1161/JAHA.117.007185 |