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Uremic Advanced Glycation End Products and Protein‐Bound Solutes Induce Endothelial Dysfunction Through Suppression of Krüppel‐Like Factor 2

BACKGROUND: Cardiovascular disease is the leading cause of morbidity and mortality in patients with end‐stage renal disease. The accumulation of uremic solutes in this patient population is associated with endothelial dysfunction and accelerated cardiovascular disease. In this study, we examined the...

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Detalles Bibliográficos
Autores principales: Saum, Keith, Campos, Begoña, Celdran‐Bonafonte, Diego, Nayak, Lalitha, Sangwung, Panjamaporn, Thakar, Charuhas, Roy‐Chaudhury, Prabir, Owens, A. Phillip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778969/
https://www.ncbi.nlm.nih.gov/pubmed/29301761
http://dx.doi.org/10.1161/JAHA.117.007566