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Suberanilohydroxamic Acid as a Pharmacological Kruppel‐Like Factor 2 Activator That Represses Vascular Inflammation and Atherosclerosis

BACKGROUND: Kruppel‐like factor 2 (KLF2) is an important zinc‐finger transcription factor that maintains endothelial homeostasis by its anti‐inflammatory, ‐thrombotic, ‐oxidative, and ‐proliferative effects in endothelial cells. In light of the potent vasoprotective effects of KLF2, modulating KLF2...

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Detalles Bibliográficos
Autores principales: Xu, Yanni, Xu, Suowen, Liu, Peng, Koroleva, Marina, Zhang, Shuya, Si, Shuyi, Jin, Zheng Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779026/
https://www.ncbi.nlm.nih.gov/pubmed/29191808
http://dx.doi.org/10.1161/JAHA.117.007134