Nitric Oxide–Dependent Feedback Loop Regulates Transient Receptor Potential Vanilloid 4 (TRPV4) Channel Cooperativity and Endothelial Function in Small Pulmonary Arteries

BACKGROUND: Recent studies demonstrate that spatially restricted, local Ca(2+) signals are key regulators of endothelium‐dependent vasodilation in systemic circulation. There are drastic functional differences between pulmonary arteries (PAs) and systemic arteries, but the local Ca(2+) signals that...

Descripción completa

Detalles Bibliográficos
Autores principales: Marziano, Corina, Hong, Kwangseok, Cope, Eric L., Kotlikoff, Michael I., Isakson, Brant E., Sonkusare, Swapnil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779028/
https://www.ncbi.nlm.nih.gov/pubmed/29275372
http://dx.doi.org/10.1161/JAHA.117.007157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779028/
https://www.ncbi.nlm.nih.gov/pubmed/29275372
http://dx.doi.org/10.1161/JAHA.117.007157

Ejemplares similares