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Nitric Oxide–Dependent Feedback Loop Regulates Transient Receptor Potential Vanilloid 4 (TRPV4) Channel Cooperativity and Endothelial Function in Small Pulmonary Arteries

BACKGROUND: Recent studies demonstrate that spatially restricted, local Ca(2+) signals are key regulators of endothelium‐dependent vasodilation in systemic circulation. There are drastic functional differences between pulmonary arteries (PAs) and systemic arteries, but the local Ca(2+) signals that...

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Detalles Bibliográficos
Autores principales:	Marziano, Corina, Hong, Kwangseok, Cope, Eric L., Kotlikoff, Michael I., Isakson, Brant E., Sonkusare, Swapnil K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779028/ https://www.ncbi.nlm.nih.gov/pubmed/29275372 http://dx.doi.org/10.1161/JAHA.117.007157

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