Cardiac Insulin Signaling Regulates Glycolysis Through Phosphofructokinase 2 Content and Activity

BACKGROUND: The healthy heart has a dynamic capacity to respond and adapt to changes in nutrient availability. Diabetes mellitus disrupts this metabolic flexibility and promotes cardiomyopathy through mechanisms that are not completely understood. Phosphofructokinase 2 (PFK‐2) is a primary regulator...

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Detalles Bibliográficos
Autores principales: Bockus, Lee B., Matsuzaki, Satoshi, Vadvalkar, Shraddha S., Young, Zachary T., Giorgione, Jennifer R., Newhardt, Maria F., Kinter, Michael, Humphries, Kenneth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779029/
https://www.ncbi.nlm.nih.gov/pubmed/29203581
http://dx.doi.org/10.1161/JAHA.117.007159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779029/
https://www.ncbi.nlm.nih.gov/pubmed/29203581
http://dx.doi.org/10.1161/JAHA.117.007159

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