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Cardiac Insulin Signaling Regulates Glycolysis Through Phosphofructokinase 2 Content and Activity

BACKGROUND: The healthy heart has a dynamic capacity to respond and adapt to changes in nutrient availability. Diabetes mellitus disrupts this metabolic flexibility and promotes cardiomyopathy through mechanisms that are not completely understood. Phosphofructokinase 2 (PFK‐2) is a primary regulator...

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Detalles Bibliográficos
Autores principales:	Bockus, Lee B., Matsuzaki, Satoshi, Vadvalkar, Shraddha S., Young, Zachary T., Giorgione, Jennifer R., Newhardt, Maria F., Kinter, Michael, Humphries, Kenneth M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779029/ https://www.ncbi.nlm.nih.gov/pubmed/29203581 http://dx.doi.org/10.1161/JAHA.117.007159

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