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Aberrant Iodine Autoregulation Induces Hypothyroidism in a Mouse Strain in the Absence of Thyroid Autoimmunity

We investigated factors underlying the varying effects of a high dietary iodide intake on serum T4 levels in a wide spectrum of mouse strains, including thyroiditis-susceptible NOD.H2(h4), NOD.H2(k), and NOD mice, as well as other strains (BALB/c, C57BL/6, NOD.Lc7, and B10.A4R) not previously invest...

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Detalles Bibliográficos
Autores principales: McLachlan, Sandra M., Aliesky, Holly A., Rapoport, Basil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779109/
https://www.ncbi.nlm.nih.gov/pubmed/29379895
http://dx.doi.org/10.1210/js.2017-00400