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The Orphan Nuclear Receptor Liver Homolog Receptor-1 (Nr5a2) Regulates Ovarian Granulosa Cell Proliferation

In mouse ovaries, liver receptor homolog-1 [nuclear receptor subfamily 5, group A, member 2 (Nr5a2)] expression is restricted to granulosa cells. Mice with Nr5a2 depletion in this cell population fail to ovulate. To determine whether Nr5a2 is essential for granulosa cell proliferation during follicu...

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Detalles Bibliográficos
Autores principales: Meinsohn, Marie-Charlotte, Morin, Fanny, Bertolin, Kalyne, Duggavathi, Raj, Schoonjans, Kristina, Murphy, Bruce D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779114/
https://www.ncbi.nlm.nih.gov/pubmed/29379893
http://dx.doi.org/10.1210/js.2017-00329