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Super-resolution imaging of synaptic and Extra-synaptic AMPA receptors with different-sized fluorescent probes

Previous studies tracking AMPA receptor (AMPAR) diffusion at synapses observed a large mobile extrasynaptic AMPAR pool. Using super-resolution microscopy, we examined how fluorophore size and photostability affected AMPAR trafficking outside of, and within, post-synaptic densities (PSDs) from rats....

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Detalles Bibliográficos
Autores principales: Lee, Sang Hak, Jin, Chaoyi, Cai, En, Ge, Pinghua, Ishitsuka, Yuji, Teng, Kai Wen, de Thomaz, Andre A, Nall, Duncan, Baday, Murat, Jeyifous, Okunola, Demonte, Daniel, Dundas, Christopher M, Park, Sheldon, Delgado, Jary Y, Green, William N, Selvin, Paul R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779237/
https://www.ncbi.nlm.nih.gov/pubmed/28749340
http://dx.doi.org/10.7554/eLife.27744