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Designing and building oncolytic viruses

Oncolytic viruses (OVs) are engineered and/or evolved to propagate selectively in cancerous tissues. They have a dual mechanism of action; direct killing of infected cancer cells cross-primes anticancer immunity to boost the killing of uninfected cancer cells. The goal of the field is to develop OVs...

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Detalles Bibliográficos
Autores principales: Maroun, Justin, Muñoz-Alía, Miguel, Ammayappan, Arun, Schulze, Autumn, Peng, Kah-Whye, Russell, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779534/
https://www.ncbi.nlm.nih.gov/pubmed/29387140
http://dx.doi.org/10.2217/fvl-2016-0129