The activation of G protein-coupled estrogen receptor induces relaxation via cAMP as well as potentiates contraction via EGFR transactivation in porcine coronary arteries

Estrogen exerts protective effects against cardiovascular diseases in premenopausal women, but is associated with an increased risk of both coronary heart disease and stroke in older postmenopausal women. Studies have shown that activation of the G-protein-coupled estrogen receptor 1 (GPER) can caus...

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Detalles Bibliográficos
Autores principales: Yu, Xuan, Stallone, John N., Heaps, Cristine L., Han, Guichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779678/
https://www.ncbi.nlm.nih.gov/pubmed/29360846
http://dx.doi.org/10.1371/journal.pone.0191418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779678/
https://www.ncbi.nlm.nih.gov/pubmed/29360846
http://dx.doi.org/10.1371/journal.pone.0191418

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