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Neisseria gonorrhoeae co-infection exacerbates vaginal HIV shedding without affecting systemic viral loads in human CD34(+) engrafted mice

HIV synergy with sexually transmitted co-infections is well-documented in the clinic. Co-infection with Neisseria gonorrhoeae in particular, increases genital HIV shedding and mucosal transmission. However, no animal model of co-infection currently exists to directly explore this relationship or to...

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Detalles Bibliográficos
Autores principales: Xu, Stacey X., Leontyev, Danila, Kaul, Rupert, Gray-Owen, Scott D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779692/
https://www.ncbi.nlm.nih.gov/pubmed/29360873
http://dx.doi.org/10.1371/journal.pone.0191672