Metallochaperone UreG serves as a new target for design of urease inhibitor: A novel strategy for development of antimicrobials

Urease as a potential target of antimicrobial drugs has received considerable attention given its versatile roles in microbial infection. Development of effective urease inhibitors, however, is a significant challenge due to the deeply buried active site and highly specific substrate of a bacterial...

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Detalles Bibliográficos
Autores principales: Yang, Xinming, Koohi-Moghadam, Mohamad, Wang, Runming, Chang, Yuen-Yan, Woo, Patrick C. Y., Wang, Junwen, Li, Hongyan, Sun, Hongzhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779714/
https://www.ncbi.nlm.nih.gov/pubmed/29320492
http://dx.doi.org/10.1371/journal.pbio.2003887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779714/
https://www.ncbi.nlm.nih.gov/pubmed/29320492
http://dx.doi.org/10.1371/journal.pbio.2003887

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