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Metallochaperone UreG serves as a new target for design of urease inhibitor: A novel strategy for development of antimicrobials
Urease as a potential target of antimicrobial drugs has received considerable attention given its versatile roles in microbial infection. Development of effective urease inhibitors, however, is a significant challenge due to the deeply buried active site and highly specific substrate of a bacterial...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779714/ https://www.ncbi.nlm.nih.gov/pubmed/29320492 http://dx.doi.org/10.1371/journal.pbio.2003887 |