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Improving the flux distributions simulated with genome-scale metabolic models of Saccharomyces cerevisiae

Genome-scale metabolic models (GEMs) can be used to evaluate genotype-phenotype relationships and their application to microbial strain engineering is increasing in popularity. Some of the algorithms used to simulate the phenotypes of mutant strains require the determination of a wild-type flux dist...

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Detalles Bibliográficos
Autores principales: Pereira, Rui, Nielsen, Jens, Rocha, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779720/
https://www.ncbi.nlm.nih.gov/pubmed/29468121
http://dx.doi.org/10.1016/j.meteno.2016.05.002