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Improving the flux distributions simulated with genome-scale metabolic models of Saccharomyces cerevisiae
Genome-scale metabolic models (GEMs) can be used to evaluate genotype-phenotype relationships and their application to microbial strain engineering is increasing in popularity. Some of the algorithms used to simulate the phenotypes of mutant strains require the determination of a wild-type flux dist...
Autores principales: | Pereira, Rui, Nielsen, Jens, Rocha, Isabel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779720/ https://www.ncbi.nlm.nih.gov/pubmed/29468121 http://dx.doi.org/10.1016/j.meteno.2016.05.002 |
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