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Hyaluronan production and molecular weight is enhanced in pathway-engineered strains of lactate dehydrogenase-deficient Lactococcus lactis

The potential advantages of hyaluronic acid (HA) production by metabolically-engineered Lactococcus lactis is constrained by the lower molecular weight and yield of HA obtained in these strains, compared to natural producers. Earlier studies have correlated lower HA yield with excessive lactate prod...

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Detalles Bibliográficos
Autores principales: Kaur, Mandeep, Jayaraman, Guhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779726/
https://www.ncbi.nlm.nih.gov/pubmed/29468110
http://dx.doi.org/10.1016/j.meteno.2016.01.003