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Bufalin induced apoptosis in SCC-4 human tongue cancer cells by decreasing Bcl-2 and increasing Bax expression via the mitochondria-dependent pathway

The aim of the present study was to investigate the cytotoxic effects of bufalin on SCC-4 human tongue cancer cells. Cell morphological changes and viability were examined using phase contrast microscopy and flow cytometry, respectively. The results indicated that bufalin induced morphological chang...

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Detalles Bibliográficos
Autores principales: Chou, Han-Yu, Chueh, Fu-Shin, Ma, Yi-Shih, Wu, Rick Sai-Chuen, Liao, Ching-Lung, Chu, Yung-Lin, Fan, Ming-Jen, Huang, Wen-Wen, Chung, Jing-Gung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779878/
https://www.ncbi.nlm.nih.gov/pubmed/28983595
http://dx.doi.org/10.3892/mmr.2017.7651