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Defective insulin signaling and the protective effects of dimethyldiguanide during follicular development in the ovaries of polycystic ovary syndrome

It is established that the physiological effects of insulin are primarily mediated by the insulin signaling pathway. However, a defective insulin signaling is closely associated with the clinical manifestations of polycystic ovary syndrome (PCOS), which include excess androgen levels, insulin resist...

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Detalles Bibliográficos
Autores principales: Wang, Fan, Wang, Shaobing, Zhang, Zhenghong, Lin, Qingqiang, Liu, Yiping, Xiao, Yijun, Xiao, Kaizhuan, Wang, Zhengchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779901/
https://www.ncbi.nlm.nih.gov/pubmed/28990055
http://dx.doi.org/10.3892/mmr.2017.7678