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Hypothermic machine perfusion ameliorates inflammation during ischemia-reperfusion injury via sirtuin-1-mediated deacetylation of nuclear factor-κB p65 in rat livers donated after circulatory death

Hypothermic machine perfusion (HMP) effectively reduces ischemia-reperfusion injury (IRI) in livers donated after circulatory death (DCD) when compared with cold storage (CS). However, the underlying mechanisms remain unclear. The current study aimed to investigate the cellular mechanisms by which H...

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Detalles Bibliográficos
Autores principales: Zeng, Cheng, Hu, Xiaoyan, He, Weiyang, Wang, Yanfeng, Li, Ling, Xiong, Yan, Ye, Qifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779933/
https://www.ncbi.nlm.nih.gov/pubmed/29039506
http://dx.doi.org/10.3892/mmr.2017.7738