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Caveolin-1 regulates oxidative stress-induced senescence in nucleus pulposus cells primarily via the p53/p21 signaling pathway in vitro

Previous studies have indicated that cellular senescence is a critical underlying mechanism of intervertebral disc degeneration. However, the precise mechanism by which cellular senescence accelerates disc degeneration has not been fully elucidated. Caveolin-1 has recently emerged as an important re...

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Detalles Bibliográficos
Autores principales: Ding, Lei, Zeng, Qingmin, Wu, Jingping, Li, Defang, Wang, Houlei, Lu, Wei, Jiang, Zengxin, Xu, Guoxiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780011/
https://www.ncbi.nlm.nih.gov/pubmed/29039595
http://dx.doi.org/10.3892/mmr.2017.7789