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Caveolin-1 regulates oxidative stress-induced senescence in nucleus pulposus cells primarily via the p53/p21 signaling pathway in vitro
Previous studies have indicated that cellular senescence is a critical underlying mechanism of intervertebral disc degeneration. However, the precise mechanism by which cellular senescence accelerates disc degeneration has not been fully elucidated. Caveolin-1 has recently emerged as an important re...
Autores principales: | Ding, Lei, Zeng, Qingmin, Wu, Jingping, Li, Defang, Wang, Houlei, Lu, Wei, Jiang, Zengxin, Xu, Guoxiong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5780011/ https://www.ncbi.nlm.nih.gov/pubmed/29039595 http://dx.doi.org/10.3892/mmr.2017.7789 |
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